Conflict of Interest is a situation where a person is involved in two interests that are working against each other. Every parties involved in manuscript publication needs to declare any possible conflict of interest before the manuscript is published. For example author needs to declare source of research funding to ensure that it doesn't interfere with the result. Meanwhile reviewers will also need to declare if they know, accidentally or otherwise the identity of the author which means that double-blind peer review is no longer possible. If properly declared conflict of interest will not stop a manuscript from being published by itself. In this situation final decision will be made by editor.